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Modern neuroscience shows chronic pain is often a learned brain pattern. PainApp helps you retrain your brain to break free from it.

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Your Brain Can Learn Pain — and Unlearn It

Your Brain Can Learn Pain — and Unlearn It

"Pain Reprocessing Therapy significantly reduced or eliminated chronic pain by teaching patients to reinterpret it as harmless brain activity." — JAMA Psychiatry, 2022

Summary: This study clearly shows that chronic back pain is often generated by the brain, not due to ongoing physical damage. Pain Reprocessing Therapy (PRT), which teaches patients to reinterpret their pain as harmless brain activity, significantly reduced or eliminated pain for most patients, with lasting effects even a year later. Brain scans confirmed that changing beliefs about pain also changed brain activity, further proving that chronic pain can be managed by retraining the brain.

APA Citation: Ashar, Y. K., Gordon, A., Schubiner, H., Uipi, C., Knight, K., Anderson, Z., … Wager, T. D. (2022). Effect of pain reprocessing therapy vs placebo and usual care for patients with chronic back pain: a randomized clinical trial. JAMA Psychiatry, 79(1), 13–23.

Phantom Pain Proves It’s Brain-Generated

Phantom Pain Proves It’s Brain-Generated

"Phantom limb pain is a powerful example of the brain generating pain without any physical injury." — JAMA Psychiatry, 2022

Summary: Phantom limb pain occurs when the brain continues to generate pain signals despite the limb being gone. This research found a strong link between brain reorganization and the intensity of phantom limb pain, clearly demonstrating the brain’s active role in creating pain sensations without any physical injury.

APA Citation: Flor, H., Elbert, T., Knecht, S., Wienbruch, C., Pantev, C., Birbaumer, N., … Taub, E. (1995). Phantom-limb pain as a perceptual correlate of cortical reorganization following arm amputation. Nature, 375(6531), 482–484.

Your Nervous System Can Keep Pain Alive

Your Nervous System Can Keep Pain Alive

"Even after an injury heals, your brain and spinal cord can stay on high alert — keeping pain going." — JAMA Psychiatry, 2022

Summary: This review shows that the central nervous system, including the brain, can amplify and maintain pain through a process called central sensitization. Even when initial injuries have healed, this mechanism keeps pain ongoing and intense. This highlights that many chronic pain conditions are driven by brain activity rather than physical injuries alone.

APA Citation: Ashar, Y. K., Gordon, A., Schubiner, H., Uipi, C., Knight, K., Anderson, Z., … Wager, T. D. (2022). Effect of pain reprocessing therapy vs placebo and usual care for patients with chronic back pain: a randomized clinical trial. JAMA Psychiatry, 79(1), 13–23.

Your Brain Can Learn Pain — and Unlearn It

Your Brain Can Learn Pain — and Unlearn It

"Pain Reprocessing Therapy significantly reduced or eliminated chronic pain by teaching patients to reinterpret it as harmless brain activity." — JAMA Psychiatry, 2022

Summary: This study clearly shows that chronic back pain is often generated by the brain, not due to ongoing physical damage. Pain Reprocessing Therapy (PRT), which teaches patients to reinterpret their pain as harmless brain activity, significantly reduced or eliminated pain for most patients, with lasting effects even a year later. Brain scans confirmed that changing beliefs about pain also changed brain activity, further proving that chronic pain can be managed by retraining the brain.

APA Citation: Ashar, Y. K., Gordon, A., Schubiner, H., Uipi, C., Knight, K., Anderson, Z., … Wager, T. D. (2022). Effect of pain reprocessing therapy vs placebo and usual care for patients with chronic back pain: a randomized clinical trial. JAMA Psychiatry, 79(1), 13–23.

Phantom Pain Proves It’s Brain-Generated

Phantom Pain Proves It’s Brain-Generated

"Phantom limb pain is a powerful example of the brain generating pain without any physical injury." — JAMA Psychiatry, 2022

Summary: Phantom limb pain occurs when the brain continues to generate pain signals despite the limb being gone. This research found a strong link between brain reorganization and the intensity of phantom limb pain, clearly demonstrating the brain’s active role in creating pain sensations without any physical injury.

APA Citation: Flor, H., Elbert, T., Knecht, S., Wienbruch, C., Pantev, C., Birbaumer, N., … Taub, E. (1995). Phantom-limb pain as a perceptual correlate of cortical reorganization following arm amputation. Nature, 375(6531), 482–484.

Your Nervous System Can Keep Pain Alive

Your Nervous System Can Keep Pain Alive

"Even after an injury heals, your brain and spinal cord can stay on high alert — keeping pain going." — JAMA Psychiatry, 2022

Summary: This review shows that the central nervous system, including the brain, can amplify and maintain pain through a process called central sensitization. Even when initial injuries have healed, this mechanism keeps pain ongoing and intense. This highlights that many chronic pain conditions are driven by brain activity rather than physical injuries alone.

APA Citation: Ashar, Y. K., Gordon, A., Schubiner, H., Uipi, C., Knight, K., Anderson, Z., … Wager, T. D. (2022). Effect of pain reprocessing therapy vs placebo and usual care for patients with chronic back pain: a randomized clinical trial. JAMA Psychiatry, 79(1), 13–23.

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